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Medicines that trigger spontaneous orgasms

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Remember Meg Ryan’s iconic fake orgasm scene in “When Harry Met Sally”? Now, imagine that sensation occurring spontaneously, triggered by medication. This bizarre phenomenon, documented by Taiwanese sexologists and neurologists, reveals a surprising side effect of certain drugs, particularly antidepressants.

Drug-Induced Orgasms: A Medical Anomaly

A study published in “Clinical Neuropharmacology” identified 25 individuals (18 women, 7 men) experiencing spontaneous orgasms linked to medication. Half of these cases involved antidepressant treatment. One striking example is a 46-year-old man, suffering from depression and post-traumatic head injury, who experienced multiple daily orgasms after starting antidepressants. These orgasms ceased when he stopped the medication and returned upon resumption, highlighting a direct correlation.

Characteristics of Spontaneous Orgasms

The study revealed several key characteristics:

  • Lack of Arousal: In many cases, these orgasms occurred without sexual desire or arousal.
  • Variable Intensity: The intensity ranged from less than usual to greater than usual.
  • Frequency: Some individuals experienced multiple orgasms daily, with one woman reporting up to 45 orgasms per day.
  • Triggers: Orgasms occurred during everyday activities like walking, exercising, yawning, or even sleeping.
  • Duration: Most orgasms lasted less than a minute, but some extended for hours.

Specific Cases and Triggers

A 37-year-old lawyer, treated for ADHD with bupropion, experienced heightened libido and spontaneous orgasms, including a powerful double orgasm during intercourse. A 35-year-old woman on antidepressants had a three-hour orgasm while shopping. These cases illustrate the diverse and unpredictable nature of this side effect.

Neurological Mechanisms and Patient Reactions

The precise neurological mechanisms behind these drug-induced orgasms remain unclear. However, the experience can be distressing and embarrassing for patients. Not all patients enjoy this side effect.

Importance of Patient-Doctor Communication

The study emphasizes the importance of patients and their partners reporting any sexual side effects to their doctors. This allows for potential treatment adjustments and helps doctors recognize the frequency of such occurrences.

Beyond Orgasms: Other Sexual Side Effects

Spontaneous orgasms are not the only sexual side effect of medication. Some patients, particularly those with Parkinson’s disease treated with dopamine agonists, may experience hypersexuality. Doctors should actively inquire about sexual dysfunction when treating patients with medications known to cause these issues.

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